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Medical News and Perspectives | July 23/30, 2003

JAMA. 2003;290(4):449-450. doi:10.1001/jama.290.4.449

The United Kingdom (UK) has granted a license to Roslin Institute, Edinburgh, Scotland, to create human embryos for stem cell research via parthenogenesis, a “virgin birth” technique that jolts oocytes into a fertilized state without sperm. The license also allows the institute—former home of Dolly the sheep, which died in February—and its lead cloning researcher, Ian Wilmut, PhD, to derive stem cells from embryos created for in vitro fertilization (IVF) .

These nonhuman primate eggs have developed into 8-day-old embryos via a process called parthenogenesis (Science . 2002;295:819) (Photo credit: AAAS)

It is the fourth license for embryonic stem cell research handed out by the government of the United Kingdom, but the first license allowing the creation of human embryos by any means.

Speaking at the National Institutes of Health, Bethesda, Md, Wilmut said that he supports research on all types of stem cells, whether from embryos or adult tissues.

But he added that cloned embryos offer the most promising means for identifying the origins of and treatments for genetic conditions such as amyotrophic lateral sclerosis, or Lou Gehrig disease (JAMA. 2001;285:1691-1693). Embryos created using DNA from individuals with such diseases could provide researchers with an almost unlimited supply of stem cells, each carrying the key genetic defect. Such a pool would allow scientists to undertake more, and more sophisticated, experiments than any other available technology, said Wilmut, who spoke at a conference sponsored by the General Motors Cancer Research Foundation.

INCREASING THE EGG SUPPLY

INCREASING THE EGG SUPPLY

In an interview following his talk, Wilmut said that the aims of the newly licensed research are two-fold: to improve basic stem cell culturing technologies and to increase the supply of human eggs available for research.

INCREASING THE EGG SUPPLY

Roslin will immediately begin collecting embryos donated by patients from IVF clinics, which typically create several excess embryos per pregnancy attempt. The second route to boosting the egg supply, parthenogenesis, is much more technically challenging, said Harry Griffin, PhD, acting director at Roslin.

INCREASING THE EGG SUPPLY

The process involves gathering immature eggs from donors undergoing surgery for nonfertility-related reasons and then coaxing them to maturity in the laboratory. If successful, Roslin scientists will try to glean stem cells from the parthenotes (embryos grown from unfertilized eggs).

INCREASING THE EGG SUPPLY

Roslin’s agenda is the latest in a long line of advances involving parthenogenesis. Decades ago, scientists discovered that some plants and lower animals, including insects and corals, reproduce via the technique. Because the oocytes do not complete meiosis, they contain a full complement of the parent’s chromosomes—a clone.

INCREASING THE EGG SUPPLY

SUCCESS IN PRIMATES

Then in 1936, Gregory Pincus, MD, one of the scientists involved in developing the first birth control pill, induced parthenogenesis in rabbit eggs via temperature change and chemical agents. In 2001, Michael West, PhD, and colleagues at Advanced Cell Technology (ACT), Worcester, Mass, announced the creation of human parthenotes, although many scientists expressed skepticism about the embryos’ usefulness, as they died shortly after creation. A year later, though, a team led by ACT scientists and Kent Vrana, PhD, professor of physiology at Wake Forest University School of Medicine, obtained embryonic stem cells from monkey parthenotes, an advance that sparked a wave of enthusiasm (Science. 2002;295:819).

SUCCESS IN PRIMATES

Roslin is the latest institute to ride that wave, and Wilmut expressed confidence that parthenogenic human embryos will eventually provide a rich source of stem cells for research. But constructing a steady supply of stem cells is just the first step in the research pipeline. Once collected, the cells need to be fed and kept stable.

SUCCESS IN PRIMATES

Because current stem cell lines rely on mouse “feeder” cells, in theory, Wilmut said, unknown viruses in animal feeder cells could find their way into the human cells, a concern that the US Food and Drug Administration has also raised. To avoid that possibility, scientists at Roslin are developing techniques that would rely instead on human feeder cells or, even more ambitiously, on completely cell-free media. That is, the embryonic stem cells would grow in a rich soup of organic compounds.

SUCCESS IN PRIMATES

According to an abstract posted on the Web site of the UK’s Human Fertilization and Embryology Authority (HFEA), the agency that grants stem cell research licenses, Roslin now has permission to pursue this goal, too (http://www.hfea.gov.uk/aboutHFEA/researchLicenses.htm).

TO CLONE, OR NOT TO CLONE

TO CLONE, OR NOT TO CLONE

Like Roslin, the other three UK licensees—Guy’s Hospital, London; the Institute of Stem Cell Research at the University of Edinburgh; and the London Fertility Centre—are culturing stem cells from donated IVF embryos.

TO CLONE, OR NOT TO CLONE

Under a sweeping 1990 law, the HFEA regulates all IVF and human embryo research in the United Kingdom; a 2001 update to the HFEA banned all reproductive cloning and mandated that any artificially created human embryos must be destroyed within 14 days. In March, the House of Lords ruled that despite challenges from antiabortion groups, the HFEA holds the authority to license research involving embryo creation via parthenogenesis and cell nuclear replacement, although cloning for reproductive purposes remains off limits.

TO CLONE, OR NOT TO CLONE

Wilmut did not say if Roslin would pursue a license to attempt the more controversial nuclear replacement technique, the method used to create Dolly. In nuclear replacement, genetic material from an adult cell is transplanted into an oocyte, which is stimulated and begins embryonic development—a procedure that succeeds only rarely. While parthenogenesis allows cloning of reproductive-aged females, nuclear replacement could, hypothetically, clone any person, alive or dead (if viable DNA can be recovered).

TO CLONE, OR NOT TO CLONE

While tightly controlled in the United Kingdom, cloning research in the United States is largely unregulated. Bills outlawing the creation of cloned embryos for reproduction—and also for research, depending on the bill—have stalled in the US Congress, leaving the cloning landscape wide open for private companies. However, restrictions apply to researchers receiving federal funds, who may work with a handful of approved but largely uncharacterized embryonic stem cell lines and are not allowed to create cloned human embryos (JAMA. 2003; 289:1092).

https://ce399.wordpress.com/2012/06/14/uk-licenses-human-embryo-creation-jama-72003/

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Tarn - mutual eye-rolling's avatar

Judge: 'Why did you do this?'

Defendant: 'Because I could.'

Judge: 'That's okay then. Case dismissed.'

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Jul 24, 2022
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Tarn - mutual eye-rolling's avatar

I have been hearing that Huxley was a eugenicist. Some sort of bad egg.

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Stegiel's avatar

He was. Also worked with CIA and recruited Tim Leary. Which in no way alters the power of the art and thought. One merely notes biases. Mileus have us. Childhoods too. Family. Placement in social order. Blind spots. Usually absence of

Empathy and Compassion with Anglo-Saxons

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Tarn - mutual eye-rolling's avatar

We do have truisms along those lines:

Everyman for himself.

It's a dog eat dog world.

There's one (a sucker) born every minute.

Eat or be eaten.

And it took me no time at all to think of those.

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Stegiel's avatar

Say we slip energy use wise to 1700 A.D.. Could NZ support her population? The thought strayed in this afternoon with the fog that collapse could crash deeply. We shop in the Marina grocery store with a view of the Bay and Golden Gate. Got thinking about inventory. Completely out of choices in the Egg department-not restocked. Meats looked thin.

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Tarn - mutual eye-rolling's avatar

No shortages here yet.

Just inflation.

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Lorraine Thomas's avatar

It is no accident….Satan and man have worked in tandem to destroy civilization for thousands of years! Man…inspired by the Devil…is under the illusion that he can get along quite well without God…who’s foolishness… ( if God could be foolish )…..is wiser than all of mans wisdom put together! We’re close to the end of human history…where all of Satans foolish designs…adopted by man…. are about to be accomplished! Only the godly wise will survive!

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Stegiel's avatar

Eschatology is my field for a few years now. I am reminded that Jesus reminded us. "My Kingdom is not of this world." We are mistaken to think our nations and their governors will initiate a paradise or even a peaceable Kingdom. This is the Tragedy of man.

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Lorraine Thomas's avatar

How right you are! “Man is born unto trouble as the sparks fly upward!” All because of “sin”……mans long war against his Creator!

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Stegiel's avatar

Lorraine you may find the work of the Russian philosopher Berdyaev interesting. "And so the tragedy is that the creation rebels against its creator, no longer obeys him. The mystery of the fall is the creature's rebellion against the Creator."

"The path of man's final liberation and the final realization of his vocation is the path to the kingdom of God, which is not only the kingdom of heaven, but also the kingdom of a transformed earth, a transformed cosmos." [1]

Source of literature:

1. Berdyaev N. Man and Machine. (The Problem of Sociology and Metaphysics of Technology) // "Put". - May 1933. - №38. - с. 3-38. [Electronic resource]- URL: https://masters.donntu.org/2007/kita/ovcharenko/library/berdyaev_article_01.htm (accessed: 14.12.2021).

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Tarn - mutual eye-rolling's avatar

An "underspecies" and a "superspecies". Well we don't know what the genetic modification actually means, is the spike's attack on DNA more than a health thing, is it enough to create another species, or will that be future injections.

Some have suggested that a change in personality is happening in injectees, but that could be from feeling duped, or feeling superior for having the shots, or the general crazy of the times.

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Stegiel's avatar

We do not know. We know Schwab et al want Transhumanism. We know mRNA alters DNA. We do not know. what other alterations, or changes they seek. Nor do we know what the "science" will study with the experiment of billions vaccinated. My personal thought is 5G control. And my second thought is anything goes.

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Rick Larson's avatar

Those who are driving this change also have no idea of what they produce. The odds of something positive are so small that I will type it will end in catastrophe.

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Tarn - mutual eye-rolling's avatar

I guess that there must have been a whole lot of variety in the injection batches. A very poor experiment to inject billions of guinea pig with the same concoction.

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Stegiel's avatar

I suspect that variety would be finer grained than we suspect. Perhaps each batch had one difference or each country had a special enhancement based on some variable of importance.

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Tarn - mutual eye-rolling's avatar

In some countries serialisation of the phials was contractually forbidden, which would also mean that the experimenters would be stymied from doing a finely grained analysis of outcome.

I get your suggestion of each country having its own brew, but adverse reactions are random (at this stage of amateur observation), implying that not all phials are vile.

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Stegiel's avatar

Or implying "fitness" of the target. All vials of mRNA do act the same. Most likely is some bodies can tolerate the hazard until they cannot. No autopsy. John died of winter flu.

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Tarn - mutual eye-rolling's avatar

An autopsy was carried out on a 50yr old male gym bunny in my husband's family, because of the suddenly dying.

Result: a mystery.

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Stegiel's avatar

I think this thread is going to grow on the general idea set forth of Titanism. Biotech in the hands of insane people as explained by Ponerology and Biotech as Transhumanism and Covid-19 Die Wende. https://johnwaters.substack.com/p/tyranny-by-numbers?utm_medium=reader2

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Ray Horvath, "The Source" :)'s avatar

Technological advances have just about always originated from military R&D. As such, the source was fear and the objectives were domination and efficient killing.

This must have started at the beginning of human history and "perfected" ever since...

Twenty years ago, I already conjectured the genetic attack on humans (I thought it would be race-based) and the genocide by "vaccinations," because even at that point, the propaganda was revealing enough to notice the predictive programming towards such strategies employed by the powerful in the future. At that time, I figured that if I were one of the monsters, I would release a toxin whose antidote would be in a "vaccine," which would filter out the non-compliant. After that, I could focus on attacks on certain parts of the population or cover specific areas, using the same method. I was unaware of all the other options (military radars/emitters, chemtrails, other pharmaceutical methods, and the high efficiency of western "medicine") that can be combined towards the same purpose. Either way, something that can be done is usually done by someone. It's happening.

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Tarn - mutual eye-rolling's avatar

You had me worried there for a minute Ray, with "filtering out the non-compliant".

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Ray Horvath, "The Source" :)'s avatar

That reminds me an old joke:

History class, the teacher is asking a student,

"Who occupied Rome in 412 AD?"

The student defensively, in a plaintive voice,

"Sorry, Sir, it wasn't me!"

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KW NORTON's avatar

Good thinking, writing. It’s going to take me awhile to digest all this. The ways in which I personally imagine the serial ruin of civilizations throughout history these ideas seem a natural part of our human choices. If I can figure a way backwards through the labyrinth which makes sense I’ll write about it. Use of mRNA was my first concern, before Graphene Oxide, Koch’s postulates, etc. mRNA codes for protein synthesis, travels from the cell nucleus to the cytoplasm carrying DNA-mandated instructions for protein synthesis. What could go wrong?

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Stegiel's avatar

As a writer and reader of SF one may say I am sensitized to the emerging global Dystopia. Earth Abides was my first virus book. Then Andromeda strain. Then the book that inspired Omega Man-I am Legend. Toss in the atomkrieg books and the young mind was saturated.

However in the days of the internet, on a strange site, Godlike Productions, long ago, first came a story of ET needing human genetics because of a "mistake" in 2000 they thought that altered them as they went to the stars. . Dan began to work as part of the Aquarius-J-Rod team6 which was tasked with the problem of figuring out why the J-Rods (commonly called Grays)7 were suffering from a debilitating medical condition that affected their nerves. Part of this work involved taking physical tissue samples from the J-Rod housed deep below S-4 in a 'Clean Sphere' designed to support his atmospheric and environmental needs.

It soon became apparent that these Extraterrestrials were not all that different from us. In fact, as communications improved, it was learned that they are not so much space travelers as time/space travelers, using a small planet in the Gliese System as a local base (approximately 15 light years from Earth) where they can stage for their trips here. Using Looking Glass technology (which might be more properly called Stargate technology) they traveled in time from a Human future, which is real to them, but only potential for us. https://projectcamelot.org/dan_burisch_summary.html

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Tarn - mutual eye-rolling's avatar

I am surprised that they admitted upfront about the mRNA.

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Stegiel's avatar

Admit a little. Hide more.

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Rick Larson's avatar

The Luddites reacted.

Excellent report - its all going to end in catastrophe. Those at the top of the hierarchy will suffer the torturous flip the most as they are both mentally and physically impaired by the power of money.

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Ray Horvath, "The Source" :)'s avatar

It's been clear how mRNA injections work ever since one had to look them up at the time they were announced about two years ago.

It is a problem that various research groups find various things in the batches available for them. Perhaps checking out their funding would reveal where they are coming from.

https://rayhorvaththesource.substack.com/p/mrna

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Tarn - mutual eye-rolling's avatar

Good post Stegiel. Hits a head on the nail.

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Tarn - mutual eye-rolling's avatar

Wonder what PV means about dragging in the question of art.

*Art* has been sorely absent, (from where I am sitting anyway) this whole plandemic. Some good memes, some good cartoons.

What are we missing, is everything art-wise just the internet now and social media. (Edit: and film.)

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Stegiel's avatar

PV-What does this have to say about the function of art in relation to science?

PV: Art is initiatory. Pointillism is already an analysis of light. The Impressionists did cloning too – Monet’s series. The art of these periods, it’s prophetic somehow. I don’t know if it is still the case today, but certainly since Romanticism, since the 18th and 19th centuries in any case, the arts have been, in the profane sense of the word, prophetic of political mutations. One can say that in some way the arts had a role comparable to religion and philosophy, but the role of art was not to put on trial the way philosophy and religion did; the role of art was to announce prophetically what was happening. I think Romanticism as well as Surrealism announced as much. I recall that Surrealism is born after WWI and is sort of the child of the war, whereas Futurism straddles WWI: it is 1910, so just before. But between Futurism and Surrealism, the prophecy of modern times, the period we are talking about, passes through Kafka, who is the profane prophet par excellence, the prophet of extermination. Because somehow it is the question of extermination which is raised. Extermination has been undertaken over and over since the 19th century. There was the extermination of the concentration camps, Auschwitz; there has been the atomic extermination, Hiroshima. And

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Tarn - mutual eye-rolling's avatar

For our times cinematography has been the prophet of doom.

Many say that the Globalists forewarned of their agenda through Hollywood.

Maybe. But maybe it was that prophesizing of the artist.

Many transhuman movies actually had a regular guy come in and, at the last minute of course, see the light and save humanity.

PV reminds me of Kafka's story about a man waking up as a beetle - that's a bit of a foretelling too lol.

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Stegiel's avatar

PV wrote on the science or logic of speed. He is interested in the Accident. When you invent the ship you invented the integral accident. He wrote on light in cinema and TV in his book Pure War. I read that book when it first hit print in 1983...A pity really I never devoted myself to a close study like a Ph.D to his thought

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Stegiel's avatar

https://mobile.twitter.com/theno1waffler/status/1549834043738525701. World Economic Forum Video From 2015 Discussing the Ability of an mRNA Medical Procedure to Permanently Change the Genetics of the Subject and It’s Offspring:

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Tarn - mutual eye-rolling's avatar

I see the PV relevance.

Nothing stopping the bomb.

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Rick Larson's avatar

As opposed to ethics, morals, and nature itself.

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Tarn - mutual eye-rolling's avatar

I see that "Pure War" had a 2008 reprint and paperback still available.

Have ordered "Information Bomb" from local library; it being the only PV book they hold.

Hope I am still capable of reading a book. Haha.

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Stegiel's avatar

Might be free. I use Pdf finder or Bookzz for free books. Then Internet Archives. Now pdf library built up since 2003 of about 1500 free books. Sometimes I just pick an author-Coleridge say--and download his work and academic study. With sleuthing and time much can be found free.

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Tarn - mutual eye-rolling's avatar

Thanks for the tip.

I have noted it for later.

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Rick Larson's avatar

I have a thought this was all preordained from cave art.

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Tarn - mutual eye-rolling's avatar

Plato's cave. LOL

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Rick Larson's avatar

Hahahaha! Just tending a garden will wake up the soul. Hahahaha! Most are no longer capable, at least not a natural garden, one not devoted to all things made by machines, and will die soon!

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Tarn - mutual eye-rolling's avatar

That's a whole lot of emotion in a few lines Rick.

Cheers, Cairn.

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Stegiel's avatar

We by having free will create the accident when we create. No airline can crash until invented. All airlines are built to fly but hold the possibility of crashing by accident.

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Tarn - mutual eye-rolling's avatar

We are watching a train crash.

Things have been hurtling in this direction, whether as part of a concerted conscious plan or natural deterioration of morals.

That's the question, how to rewind without going to the Dark Ages.

But no, not the WEF's Build Back Better which is the actual train crash.

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Stegiel's avatar

The apex of power pyramid is the hand on the throat of all below. The changes are too great too fast.

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